Antiphospholipid Antibody–Associated Young Stroke

Word Count : 2800

Objectives to cover: 

  • Introduction: Overview of stroke in young adults and the role of antiphospholipid antibodies as a rare but significant cause.

  • Epidemiology: Prevalence of antiphospholipid syndrome (APS) among young stroke patients.

  • Pathophysiology: Mechanism of hypercoagulability leading to arterial thrombosis in APS.

  • Risk Factors: Contributing factors such as autoimmune disorders, smoking, and hormonal therapy.

  • Clinical Presentation: Typical neurological deficits and patterns of stroke in APS.

  • Diagnostic Evaluation: Role of imaging and laboratory tests including lupus anticoagulant and anticardiolipin antibodies.

  • Management: Acute stroke treatment and long-term anticoagulation strategies.

  • Prognosis and Complications: Risk of recurrence and long-term neurological outcomes.

  • Conclusion: Importance of early recognition and targeted therapy to prevent recurrent strokes.

Reference: IEEE