Incidental GIST Identified in Minimally Invasive Surgery

Word Count : 1500

Objectives to cover: 

  • Introduction – Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors of the gastrointestinal tract often detected incidentally.

  • Epidemiology – GISTs most commonly arise in the stomach and small intestine, typically affecting middle-aged and older adults.

  • Clinical Presentation – Many GISTs remain asymptomatic and are discovered during imaging or unrelated surgical procedures.

  • Intraoperative Finding – During minimally invasive surgery, a small submucosal mass may be unexpectedly visualized.

  • Diagnostic Evaluation – Histopathology and immunohistochemistry (CD117/DOG1 positivity) confirm the diagnosis of GIST.

  • Risk Stratification – Tumor size and mitotic index are key factors in assessing malignant potential.

  • Surgical Management – Complete surgical excision with clear margins is the standard treatment approach.

  • Prognosis and Follow-up – Early incidental detection generally carries a favorable prognosis with regular surveillance.

  • Conclusion – Incidental GIST identified during minimally invasive surgery highlights the importance of careful intraoperative assessment and appropriate management.

Reference: IEEE